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The specific criteria vary by indication: For T2D (Ozempic/Mounjaro): Documented T2D diagnosis, HbA1c at or above 7%, prior treatment history (typically metformin unless contraindicated), and prescriber documentation of clinical management

Clinically, I think of these medications as potentially powerful adjuncts but not replacements for therapy, behavioral change, or deeper work around coping and meaning, he said

High post-meal glucose spikes despite adequate fasting glucose control

It is believed that imbalanced gut microflora may contribute to CKD progression, but CKD also appears to disrupt the intestinal environment and affect microbiome composition